Análise de marcadores tumorais no município de Serrinha-Ba/Brasil
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Abstract
Cancer is a disease that has increased quite considerably around the world, mainly from the last century. Thus, the use of tumor markers is helping more and more as an aid to diagnosis, as well as cancer relapsed and other factors. The tumor markers, however, are cellular, structural and biochemical components that may define the cellular and molecular changes in both normal cells and those associated with malignant transformation. Ideally, a tumor marker should rise in the blood occur only in presence of tumors and not when the individual present some other disease. The clinical value for any tumor marker will always depend on their sensitivity, specificity, and its clinical application. Hitherto known markers are not sensitive enough in population screening or primary diagnosis of cancer because not all tumors are efficient markers producers. However, the aim of this study is to analyze the trends of changes in serum levels of biological tumor markers (AFP, CA 19.9, CEA) in 200 users of the Unified Health System (SUS), who attends the laboratory unit of public health (Laboratory Municipal Regional Reference / Lacen Serrinha of Serrinha-BA municipality aged 30 and 70 and residing in the same city. The tumors marker AFP and CA 19.9 were the ones with the highest percentage of elevation among the study population, which is in accordance with the literature consulted.
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